The business case for adoption of eXtended Reality (XR) technology within Industry 4.0 is compelling… increased productivity, training effectiveness, engagement, retention, and motivation, with decreased time to proficiency, human error, downtime, and operating costs. Yet, adoption has been languid, as barriers to XR implementation abound. While high-quality, affordable, wearable augmented reality (AR) and VR (virtual reality) gear are readily available, high-value use cases are little understood; start-up costs are high; the requisite supply of compelling content and anticipated high-end user experience are yet to be realized; there are a paucity of empirical studies on learning outcomes and performance gains; there are no readily available tools to support scalability and sustainability; and cybersickness is still a challenge. To facilitate adoption, XR ecosystems are needed that can readily overcome the current lack of content by automating the production process. At the same time, content must be coupled with XR enablers, including new XR-specific user experience design paradigms that are contextually rich, intuitive, and uniquely suited to 3D interaction, along with the ability to plug-in to digital twins that reflect the reality and complexity of real-world systems to fuel predictive analytics and close the loop between operator and system. The future of industry relies on the ability of such XR ecosystems and XR enablers to generate value-added use cases that not only justify adoption costs but proportionally outweigh them. This tutorial will dive into how enterprises could derive immense value from XR adoption by providing insights into: key drivers of XR adoption; key barriers to XR adoption; value-added uses cases; and guidelines on where an organization might consider starting their XR adoption journey.