Current training for deployable medical personnel occurs in the field through on-the- job training and focuses on the acquisition of procedural knowledge. This severely limits the capability of training organizations to rapidly produce "mission ready" personnel for the field, and hinders mission performance for deploying medical forces, both ground based and air evacuation teams. Medical professionals need a means of accelerating the acquisition of expertise in decision-making and team coordination that underlies responses to chemical, biological and radiological (CBR) threats. This paper describes the use of cognitive approaches to determine the training scenarios needed and the content to be included in simulation-based training to address the potential threat environments where ground based medical crews and aerospace medical personnel are expected to operate. The use of simulation based training will provide medical personnel with realistic, high fidelity, mission-oriented training in critical medical skills, decision-making and team coordination for emergency response and rapid deployment. The simulations developed will be hosted in multiple delivery media to facilitate their use at the home duty station, on transport aircraft en-route to deployment, at ground bases and in theater. A conceptual high-level design and demonstration has been developed in this Phase I SBIR effort to prove the concept for the training technologies and simulation.