The US and our Multinational partners are investing heavily in the development of model-based systems engineering and digital engineering capabilities to increase their concept exploration agility and analyses of alternative potential solutions in very detailed software models as opposed to expensive hardware prototypes. This Focus Event will take a broad innovation application perspective on digital twinning and digital engineering and will examine trends at the multinational level with several national use cases. Given the growing trend toward more model based engineering and exploration, it is clear that different national interests drive this trend in strikingly different and exciting ways. In many cases, remarkable efficiencies have been realized and the process of moving from digital models to actual fieldable hardware has substantially decreased the time from idea to actual fielding by several years! Several SMEs who are actively involved in their country’s digital engineering enterprise discuss their successes, challenges, and potentials for digital engineering today and in the near future.