Current methods employed for the manufacturing of manikins and analogue simulators are lacking accurate physiology, and do not benchmark against human tissue properties. We have created cost-effective, simulated, and representative (human) high-fidelity bench top models and manikins with realistic mechanical properties built from human biomechanics data. Our program creates analogue tissue models with material properties representative of human tissue that can be designed and benchmarked against our Human tissue-property database. Such models are generated from, and can be registered with, patient-specific VR 3-D models. A simple organosilicate is used as a template for the development of human tissue models. Organosilicate films that are exposed to an ultraviolet light source have at least a 10% or greater improvement in their mechanical properties (i.e., material hardness and elastic modulus) compared to as-deposited film. Additionally, organosilicates are ideal due to their x-ray reflectivity, making them good clinical model substitutes for ultrasound and fluoroscopy applications. Moreover, this soft matter can be layered like human tissue with no space between layers and wrinkles very similar to human skin. The goal of this project has the potential to replace animal models. The tissues can be shot, exposed to blast pressures, cut, burned, etc, and then "surgically repaired." They can be used independently or as hybrid models attached to standardized patients or confederates in training environments. They are relatively cheap, rapid to produce, and greatly exceed current simulator fidelity. The production methodology allows for imbedding of sensors or fiducials to capture data for user's performance relative to collision forces and location.