Effective cross-boundary teaming is imperative in today's operational environment. Evidence shows that we are shifting from routine individual tasks to more complex cognitive tasks in a team-based environment, increasing the demand on cross-functional teams. This increased level of complexity demands a new approach to forming and launching teams in both the military and in industry. Current military doctrine primarily deals with hierarchical unit teams and discusses the need for effective joint, interagency, intergovernmental, and multinational (JIIM) teams, but it does not specifically address methods to manage the complex cognitive tasks these teams perform. Emerging military mission command doctrine is a slight improvement; it talks a good game, but it offers little in the way of practical approaches for building common and shared purpose, trust, and team competencies. In 2009, we introduced the Teams of Leaders approach while working with JIIM teams at European Command (EUCOM). We demonstrated its usefulness in decreasing the time it takes a team to form, launch, and reach a high level of performance. In succeeding years, we have improved both our team development approach and the means by which we measure success. This paper reports on the progress of that work and expands the approach to both industry and healthcare, as well as the Army force generation (ARFORGEN) cycle. A structured Team Launch Workshop is introduced, which increases shared understanding and builds trust in both established teams and newly forming teams, along with a set of evaluation criteria designed to measure the seven dimensions of a high-performing team. Using results from four case studies (an interagency team, a U.S. Army Brigade Combat Team, an interdisciplinary health research team, and a rural health consortium), we discuss the components of high-performing teams, provide metrics to measure high performance, offer practical strategies to increase communication and collaboration, and suggest effective ways to apply information technology and knowledge management to improve the reach and corporate memory of leader teams.