The V-22 Osprey aircraft is envisioned as a versatile and complex weapon system that will offer unprecedented mission flexibility for the Army, Navy, Air Force and Marine Corps well into the next century. The V-22 will incorporate advanced technology in its composite airframe, aerodynamics, avionics, and cockpit design, and will provide the United States with a highly mission capable aircraft. Along with the system's unique flight characteristics and advanced technology underlying its construction and suite of mission systems, an expanded set of challenging new requirements for training system design is rapidly emerging. The degree to which the services and the training industry can successfully anticipate, identify and address the requirements for optimal training will largely determine the ultimate effectiveness of the V-22. This paper reviews major considerations in the V-22 training system development to date, examines some of the more salient training issues, and challenges the training systems community to develop innovative solutions that capitalize on advanced technology and maximize training effectiveness.